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Methuosis inducer 1

CAS No. 2240205-30-3

Methuosis inducer 1( —— )

Catalog No. M20667 CAS No. 2240205-30-3

Methuosis inducer 1 is a potent methuosis inducer with nticancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Methuosis inducer 1
  • Note
    Research use only, not for human use.
  • Brief Description
    Methuosis inducer 1 is a potent methuosis inducer with nticancer activity.
  • Description
    Methuosis inducer 1 is a potent methuosis inducer with nticancer activity.
  • In Vitro
    Methuosis inducer 1 (Compound 13) shows a broad spectrum of cytotoxicity against a panel of human cancer cell lines with IC50 values of 0.326±0.026 μM, 1.370±0.061 μM, 1.662±0.128 μM, 1.892±0.092 μM, 1.571±0.066 μM, 2.268±0.100 μM, 2.611±0.739 μM, 1.008±0.042 μM, 1.566±0.015 μM, and 1.197±0.344 μM for A375, SK-MEL-28, SK-MEL-30, A549, MDA-MB-231, MDA-MB-435S, MCF-7, HCT116, BGC823, HepG2 cells, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    methuosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2240205-30-3
  • Formula Weight
    487.48
  • Molecular Formula
    C27H20F3N5O?
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (51.28 mM)
  • SMILES
    Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1Nc1cc(nc2[nH]ccc12)-c1cccnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wei H Xihuan S Yunzhan L et al. Discovery and Identification of Small Molecules as Methuosis Inducers with In Vivo Antitumor Activities[J]. Journal of Medicinal Chemistry 2018:acs.jmedchem.8b00753-.
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